Pathobiology of Human Disease States

Course Information & Schedule


​Welcome to the Homepage for the Markey Pathway course at Washington University School of Medicine.  
The course meets every Tuesday and Thursday during the fall semester.  Markey students should register for 2.0 units of L41 Bio 5191. 

**Please note that acceptance into the Markey Pathway is required to attend the course**
Information about the course & how to apply can be found at:
http://dbbs.wustl.edu/curstudents/SpecialEmphasisPathways/Pages/Markey.aspx

Course Location: Farrell Learning & Teaching Center, Room 205 (FLTC 205), unless noted on the schedule*
Course Dates:  08/30/2022 - 11/22/2022 Tuesdays & Thursdays ONLY
Course Time:  1:30 PM - 3:00 PM, Unless Noted on the Schedule*

Class attendance is required.
Please check the schedule for class time changes or alternate locations (changes will be displayed in red).

Fall 2022 Class Topics:
Module 1: Diabetes (August 30 – September 22, 2022)
Module 2: Kidney Disease (September 27 – October 20, 2022)
Module 3: Immunotherapy (October 25 – November 17, 2022)

Mandatory Clinical Mentorship Orientation – Tuesday, November 22, 2022 from 2:00 pm - 3:00 pm (FLTC 205)

Module 1 - Diabetes

Module Leader:  Tom Baranski, MD, PhD Professor of Medicine and Developmental Biology, Division of Endocrinology

Date/Time

 

Location

Speaker

Title

Patient Visitor (Y/N)

Tues, Aug 30, 2022

1:30 – 3:00 pm

FLTC 205

Colin Nichols, PhD

Carl Cori Professor, Department of Cell Biology and Physiology

Director, Center for the Investigation of Membrane Excitability Diseases

Monogenic Diabetes

 

Thurs, Sep 1, 2022

1:30 – 3:00 pm

FLTC 205

Kevin Bauerle, MD, PhD

Instructor in Medicine

Division of Endocrinology

Obesity and Insulin Resistance

 

Tues, Sep 6, 2022

1:30 – 3:00 pm

FLTC 205

Paul Hruz, MD, PhD

Associate Professor of Pediatrics

Divisions of Cell Biology & Physiology and Endocrinology and Diabetes

Insulin Action-lessons from Transgenic Animals

 

Thurs, Sep 8, 2022

1:30 – 3:00 pm

FLTC 205

Tom Baranski, MD, PhD

Professor of Medicine and Developmental Biology

Division of Endocrinology

Complications of Diabetes

Y

Tues, Sep 13, 2022

1:30 – 3:00 pm

FLTC 205

Fumi Urano, MD, PhD

Samuel E. Schechter Professor of Medicine, Professor of Medicine and of Pathology and Immunology

Division of Endocrinology

Wolfram Syndrome

Y

Thurs, Sep 15, 2022

1:30 – 3:00 pm

FLTC 205

Janet McGill, MD, MA, FACE

Professor of Medicine

Division of Endocrinology

Introduction to Clinical Diabetes

Y

Tues, Sep 20, 2022

1:30 – 3:00 pm

FLTC 205

Jeff Millman, PhD

Associate Professor of Medicine and Biomedical Engineering

Division of Endocrinology

Pluripotent Technologies and Beta Cells

 

Thurs, Sep 22, 2022

(Wrap-up)

1:30 – 3:00 pm

FLTC 205

All Speakers (if available)

Faculty Overview and course discussion -        Lunch served

 

Module 2 - Kidney Disease

Module Leader: Carmen Halabi, MD, PhD Assistant Professor of Pediatrics, Division of Nephrology

Date/Time

Location

Speak​er

Title

Patient Visitor (Y/N)

Tues, Sep 27, 2022

1:30 – 3:00 pm

FLTC 205

Field Trip

Dialysis Center*

Carmen Halabi, MD, PhD

Assistant Professor of Pediatrics, Division of Nephrology

 

Introduction to kidney disease/tour of the pediatric dialysis unit

 

Y

Thurs, Sep 29, 2022

1:30 – 3:00 pm

FLTC 205

Michael Rauchman, MDCM

Chromalloy Professor of Medicine,

Division of Nephrology

 

Genetic basis of congenital anomalies of the kidney and urinary tract

 

 

Tues, Oct 4, 2022

1:30 – 3:00 pm

FLTC 205

Andrew Malone, MB, BCh

Assistant Professor of Medicine, Transplant Nephrology,

Division of Nephrology

 

Kidney disease progression

 

 

Thurs, Oct 6, 2022

1:30 – 3:00 pm

FLTC 205

Parker Wilson, MD, PhD

Assistant Professor of Pathology & Immunology

 

Multi-omic analyses of human diabetic kidney disease

 

 

Tues, Oct 11, 2022

No Class – Fall Break

n/a

n/a

 

n/a

 

n/a

Thurs, Oct 13, 2022

1:30 – 3:00 pm

FLTC 205

Leslie Gewin, MD

Associate Professor of Medicine,

Division of Nephrology

Application of single cell technologies in kidney transplantation

 

 

Tues, Oct 18, 2022

1:30 – 3:00 pm

FLTC 205

Jeff Miner, PhD, FASN

Eduardo and Judith Slatopolsky Endowed Professor of Medicine,

Division of Nephrology

 

Novel therapies for Alport’s syndrome

 

 

Thurs, Oct 20, 2022

(Wrap-up)

1:30 – 3:00 pm

FLTC 205

All Speakers (if available)

Faculty Overview and course discussion -        Lunch served

 

Module 3 - Immunotherapy

Module Leaders: 

Nathan Singh, MD, MS   Assistant Professor of Medicine, Division of Oncology
Todd Fehniger, MD, PhD   Professor of Medicine, Division of Oncology

Date/Time

Location

Speaker

Title

Patient Visitor (Y/N)

Tues, Oct 25, 2022

1:30 – 3:00 pm

FLTC 205

​Nathan Singh, MD

Assistant Professor,  

Department of Medicine,

Division of Oncology

 

Title

 

Y

Thurs, Oct 27, 2022

1:30 – 3:00 pm

FLTC 205

Carl DeSelm, MD, PhD

Assistant Professor,

Department of Radiation Oncology

 

Title

 

 

Tues, Nov 1, 2022

1:30 – 3:00 pm

FLTC 205

Todd Fehniger, MD, PhD

Professor,

Department of Medicine,

Division of Oncology

 

Title

 

Y

Thurs, Nov 3, 2022

1:30 – 3:00 pm

FLTC 205

Greg Wu, MD, PhD

Associate Professor,

Department of Neurology

 

Title

 

Y

Tues, Nov 8, 2022

1:30 – 3:00 pm

FLTC 205

Jeff Ward, MD, PhD

Assistant Professor,  

Department of Medicine,

Division of Oncology

 

Title

 

Y

Thurs, Nov 10, 2022

1:30 – 3:00 pm

FLTC 205

Amanda Cashen, MD

Professor,

Department of Medicine,

Division of Oncology

 

Title

 

Y

Tues, Nov 15, 2022

1:30 – 3:00 pm

TBD*

Field Trip!

 

Title

 

 

Thurs, Nov 17, 2022

(Wrap-up)

1:30 – 3:00 pm

FLTC 205

All Speakers (if available)

Faculty Overview and course discussion -        Lunch served

 

Mandatory Clinical Mentorship Orientation

Date/Time

Location

Speaker

Title

Tues, Nov 22, ​2022

2:00 pm – 3:00 pm*

FLTC 205

Ryan Fields, MD

Professor of Surgery

Mandatory

Clinical Mentorship Orientation

Past Course Modules

Year Modules
1992 Sickle Cell Anemia
Malaria
Diabetes
1993 Cystic Fibrosis
Coronary Artery Disease
AIDS
1994 Sickle Cell Anemia
Emphysema
Acute Leukemia
1995 Multiple Endocrine Neoplasia
Undue Susceptibility to Infection
Alzheimer’s Disease
1996 Sickle Cell Disease
Multiple Sclerosis
Epstein Barr Virus
1997 Osteoporosis
Thrombophilia
Congenital Malformations
1998 Sickle Cell Disease
Hepatitis C
Chronic Myelogenous Leukemia
1999 Rheumatoid Arthritis
AIDS
Prostate Cancer
2000 Sickle Cell Disease
Epstein Barr Virus
Heart Failure
2001 Alzheimer’s Disease
Chronic Myelogenous Leukemia
SLE (Lupus)
2002 Heart Failure
Diabetes
Mellitus Preeclampsia
2003 SLE/Rheumatoid Arthritis
Chronic Myelogenous Leukemia
Asthma
2004 AIDS
Heart Failure
Preeclampsia
2005 Alzheimer’s Disease
Breast Cancer
Rheumatoid Arthritis
2006 Sickle Cell Anemia
Congestion Heart Failure
High Risk Pregnancy
2007 Rheumatoid Arthritis
Chronic Myelogenous Leukemia
Alzheimer’s Disease
2008 Cardio Disease/Heart Failure
Diabetes & Metabolism
Osteoporosis/Other Bone Disorders
2009 Sickle Cell Anemia
AIDS
Major Depressive Disorders
2010 Alzheimer’s Disease
Cardio Disease/Heart Failure
Diabetes
2011 Chronic Myelogenous Leukemia
Cystic Fibrosis
High Risk Pregnancy
2012 Rheumatoid Arthritis
Cardiovascular Disease
Malaria
2013 Diabetes
High Risk Pregnancy
Depression
2014 Translating Global Health
Cardiovascular Disease
Chronic Myelogenous Leukemia
2015 Immunotherapy
High Risk Pregnancy
Alzheimer’s Disease
2016 Evidence Based Medicine/Sickle Cell Disease
Diabetes
Cardiovascular Disease
2017 Immunotherapy
Alzheimer’s Disease
Hearing Loss
2018 High Risk Pregnancy
Pain Management
Cardiovascular Disease
2019 Immunotherapy
Diabetes
Retina
2020 Alzheimer’s Disease
Hearing Loss
Cardiovascular Disease
2021 Sickle Cell Disease
High Risk Pregnancy
Pain Management

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