Erin Wang (MSTP in PhD training)

  • Auburn, CA

  • California Institute of Technology (2018)

  • Molecular Microbiology and Microbial Pathogenesis

  • Christina L. Stallings, Ph.D.

  • Effects of MTI’s on Mtb lipid composition and role of CarD

  • erwang@wustl.edu

Research

For my project I am investigating the effect of the molecular tolerance inhibitor C10 on the lipid composition of the Mycobacterium tuberculosis cell wall during hypoxia. Previous members of the lab observed that MTI’s blocked major changes in lipid composition that typically occur during hypoxia. I am studying how this may impact Mtb biofilm formation and resistance. I am also studying the transcriptional regulator CarD. We are interested in how specific mutations affects its ability to regulate transcription and the connection between transcription, cellular metabolism, antibiotic resistance, and cellular morphology.

Graduate Publications:

Bennion BG, Croft CA, Ai TL, Qian W, Menos AM, Miner CA, Frémond ML, Doisne JM, Andhey PS, Platt DJ, Bando JK, Wang ER, Luksch H, Molina TJ, Roberson EDO, Artyomov MN, Rösen-Wolff A, Colonna M, Rieux-Laucat F, Di Santo JP, Neven B, Miner JJ. 2020 STING Gain-of-Function Disrupts Lymph Node Organogenesis and Innate Lymphoid Cell Development in Mice. Cell Rep, 31(11):107771.

Miner JJ, Platt DJ, Ghaznavi CM, Chandra P, Santeford A, Menos AM, Dong Z, Wang ER, Qian W, Karozichian ES, Philips JA, Apte RS. 2020 HSV-1 and Zika Virus but Not SARS-CoV-2 Replicate in the Human Cornea and Are Restricted by Corneal Type III Interferon. Cell Rep, 33(5):108339.

Last Updated: 9/19/2019 6:45:34 PM

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