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Dana R. Abendschein, Ph.D.
- Inhibition of coagulation and platelet activation without bleeding, and identification of unstable plaque
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Yousef Abu-Amer, Ph.D.
- Investigating molecular mechanisms underlying inflammation-induced degenerative skeletal diseases including joint degeneration, inflammatory arthritis and osteolysis
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Nada A. Abumrad, Ph.D.
- The molecular mechanisms regulating utilization of fatty acids
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Joseph J.H. Ackerman, Ph.D.
- Magnetic resonance spectroscopy and imaging of intact functioning biological systems
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Gustav Akk, Ph.D.
- Function and modulation of transmitter-gated ion channels
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Ream Al-Hasani, Ph.D.
- Understanding the endogenous opioid systems to defeat addiction, ameliorate affective disorders, and relieve chronic pain.
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Usha P. Andley, Ph.D.
- Small heat shock protein functions in ocular systems and stress
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Ghazaleh Ashrafi, Ph.D.
- Uncovering novel regulators of glycolytic and mitochondrial metabolism at the synapse and their role in the pathology of Alzheimer’s disease
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Kareem Azab, Ph.D.
- We investigate the mechanisms of neoplasia and metastasis, and develop targeted drug-delivery-systems for cancer treatment.
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Thomas J. Baranski, M.D., Ph.D.
- Signal transduction by G proteins and pathogenesis of diabetes
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Steven Bassnett, Ph.D.
- Cell and molecular biology of the ocular lens
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Luis F.Z. Batista, Ph.D.
- Understanding the importance of telomerase in human stem and progenitor cell function and regulation
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Roger N. Beachy, Ph.D.
- Molecular and cellular basis of virus infection: Control via biotechnology
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Jeffrey J. Bednarski II, M.D., Ph.D.
- Understanding the signals that direct early B cell development
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Carlos Bernal-Mizrachi, M.D.
- Novel mechanisms of cardiovascular disease in human and mouse models with insulin resistance and type 2 DM
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Kendall J. Blumer, Ph.D.
- Tumor cell signal transduction and drug development
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Irving Boime, Ph.D.
- Placental and pituitary hormone genes
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Ron Bose, M.D., Ph.D.
- Genomics and Cell Signaling in Breast Cancer
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Jonathan R. Brestoff, M.D., Ph.D., MPH.
- Understanding how immune cells and metabolic organs interact to maintain normal metabolism and to support adaptation to physiologic challenges
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Paul C. Bridgman, Ph.D.
- Cell biology of developing nerve and muscle cells
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Steven Brody, M.D.
- Molecular and genetic mechanisms of airway epithelial cell differentiation and ciliogenesis
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Peter M.J. Burgers, Ph.D.
- Molecular Biology of DNA replication and damage response in yeast and human
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Valeria Cavalli, Ph.D.
- Cellular, Molecular and Epigenetic control of axon regeneration
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Grant Challen, Ph.D.
- Understanding the genetic and epigenetic mechanisms that regulate normal and leukemic stem cells
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Hong Chen, Ph.D.
- Combines biology, engineering, and medicine to develop ultrasound techniques for noninvasive, targeted, and personalized cancer treatment
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Yao Chen, Ph.D.
- Understanding the function of neuromodulators and sleep through the spatiotemporal dynamics of molecular signals
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Ying Maggie Chen, M.D., Ph.D.
- Understanding the molecular mechanisms of primary nephrotic syndrome (NS)
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Wayland W. L. Cheng, M.D., Ph.D.
- I am interested in the structure and function of neuronal ligand-gated ion channels, and the mechanism of channel modulation by endogenous lipids or exogenous drugs such as general anesthetics.
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Jaebok Choi, Ph.D.
- Understanding T cells and immunoregulatory networks in GvHD and GvL for the treatment of hematopoietic malignancies.
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Kyunghee Choi, Ph.D.
- Hematopoietic and Vascular Development and Regeneration
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Matt Christopher, M.D., Ph.D.
- Improve outcomes for patients with acute myeloid leukemia (AML) and other hematopoietic malignancies utilizing genomic and molecular biology techniques
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Roberto Civitelli, M.D.
- Connexins, cadherins and beta-catenin in bone cell function
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Regina Clemens, M.D., Ph.D.
- The mechanisms regulating calcium-dependent neutrophil activation
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Erika C. Crouch, Ph.D., M.D.
- Structure and function of surfactant protein D (SP-D)
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Nicholas O. Davidson, M.D.
- Mammalian gene expression: Regulation through mRNA editing and RNA stabilization
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Brian J. DeBosch, M.D., Ph.D.
- To elucidate gut and hepatic determinants of metabolic disease, including diabetes mellitus, metabolic syndrome and their complications
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David G. DeNardo, Ph.D.
- Molecular Mechanisms of Immune Regulation of Tumor Progression.
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Carl DeSelm, M.D., Ph.D.
- Dr. DeSelm clinically focuses on treating lymphoma, and is actively developing novel CAR T cell approaches to treating solid tumors, including lymphoma, pancreatic cancer and glioblastoma.
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Jorge Di Paola, M.D.
- The genetics of bleeding and thrombotic disorders and mechanisms of platelet activation
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Mary C. Dinauer, M.D., Ph.D.
- Role of leukocyte NADPH oxidase in innate immunity, inflammation, and autoimmunity
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Siyuan Ding, Ph.D.
- Understanding how rotavirus (RV), an important enteric viral pathogen, interacts with the host innate immune system in the small intestine
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Abhinav Diwan, MD, FACC, FAHA
- Transcriptional regulation of lysosome machinery under stress
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Ram Dixit, Ph.D.
- Molecular mechanisms of cytoskeleton organization and function
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Sergej Djuranovic, Ph.D.
- Molecular mechanisms of translational control
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Tamara L. Doering, M.D., Ph.D.
- Investigations of capsule synthesis and host interactions of the pathogenic fungus Cryptococcus neoformans
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Gerald W. Dorn, II, M.D.
- Cellular, Molecular, And Genetic Studies Of Cardiac Hypertrophy And Heart Failure
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Gavin P. Dunn, M.D., Ph.D.
- The immunobiology of malignant glioma with the goal of translational and clinical trial efforts in the treatment of this disease
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Susan K. Dutcher, Ph.D.
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Elliot L. Elson, Ph.D.
- Mechanical properties of reconstituted tissues; fluctuation spectroscopy of protein interactions
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Sarah England, Ph.D.
- Molecular mechanisms underlying uterine function during pregnancy
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Roberta Faccio, Ph.D.
- interactions between bone and immune cells in inflammation and cancer
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Thomas A. Ferguson, Ph.D.
- We are examining the role of the autophagy pathway in the function of the retina and its role in diseases of the eye
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Thomas W. Ferkol, M.D.
- study of inflammatory airway diseases
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Brian N. Finck, Ph.D.
- Identify novel target pathways for therapeutic treatment of obesity-related diseases including diabetes, cardiovascular disease, and fatty liver disease
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Carl Frieden, Ph.D.
- Protein structure/function relationships
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Katherine C. Fuh, M.D., Ph.D.
- Identifying pathways involved in metastasis in the context of incorporating the tumor microenvironment of ovarian cancer
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Harrison W. Gabel, Ph.D.
- Exploration of functions for neuron-specific regulators of gene expression, leveraging genes and mechanisms implicated in human neurologic disease to point us toward critical pathways in the brain.
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Gilbert Gallardo, Ph.D.
- Understand the molecular mechanisms that regulate reactive astrocytes and their neurotoxicity in
neurodegenerative diseases, including Alzheimer’s disease, by utilizing a combination of biochemistry, molecular biology, cellular models of inflammation and mouse models of neurodegenerative diseases.
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N. Gautam, Ph.D.
- Optogenetic Control of Signaling and Cell Behavior
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Robert W. Gereau, Ph.D.
- Cellular and molecular mechanisms of chronic pain, preclinical and translational research
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Daniel E. Goldberg, M.D., Ph.D.
- Biochemistry of malaria
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Misty Good, M.D., M.S.
- Focus on the cellular and molecular mechanisms involved in the development of necrotizing enterocolitis (NEC), a disease affecting the intestine of premature babies
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Jeffrey I. Gordon, M.D.
- Role of the human gut microbiome in health and disease, notably childhood undernutrition and obesity
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Gregory A. Grant, Ph.D.
- Relationship of structure to function in allosteric control mechanisms
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Abby M. Green, MD
- The etiology of genome instability in pediatric cancers and the resulting genome-protective responses, also called DNA damage responses, that are activated.
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Michael J. Greenberg, Ph.D.
- Molecular motors and the mechanobiology of heart disease
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Richard W. Gross, M.D., Ph.D.
- The molecular mechanisms through which biologic membranes participate in cellular activation processes
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Farshid Guilak, Ph.D.
- Focuses on the role of biomechanical factors in the onset, progression, and treatment of osteoarthritis and other joint diseases.
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David H. Gutmann, M.D., Ph.D.
- Leveraging neurogenetic disorders to study normal brain development, cancer, and behavior
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Carmen Halabi, M.D., Ph.D.
- Understanding how the extracellular matrix (ECM) contributes to normal arterial development and how its disruptionleads to abnormal vascular development and disease
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Dennis E. Hallahan, M.D.
- The mechanisms of cell death in normal tissues during cancer therapy
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Daniel F. Hanson, Ph.D.
- Fever as an evolutionarily adaptive regulator of immune host defense
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Jeffrey Haspel, M.D., Ph.D.
- Understand the impact of time as a biological variable in the development of critical illness such as sepsis, respiratory failure and chronic inflammatory lung disease
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Elizabeth S. Haswell, Ph.D.
- Mechanobiology with a focus on mechanosensitive ion channels
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Jason M. Held, Ph.D.
- Redox biochemistry in cell signaling and disease, Proteomics
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Keith B. Hengen, Ph.D.
- We take a "big data" approach to understanding the self-organization of neurons and networks in behaving animals.
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Andreas Herrlich, M.D., Ph.D.
- Understand the regulation of the release of growth factors and cytokines by metalloproteases cleavage from the cell surface, how it affects communication between different cell types in complex multicellular organs, and its role(s) in pathophysiology.
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Erik D. Herzog, Ph.D.
- Molecular, cellular and circuit analysis of circadian rhythms in mammals
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John E. Heuser, M.D.
- Electron microscopy of cells and molecules
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Angela Hirbe, M.D., Ph.D.
- Utilization of genomic information from sarcomas to better understand the pathogenesis of these tumors and to identify biomarkers and therapeutic targets for these aggressive cancers.
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Didier Hodzic, Ph.D.
- Role of LINC complexes (Linkers of the Nucleoskeleton to the Cytoskeleton) in nucleokinesis and neuronal migration
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Alex Holehouse, Ph.D.
- Understand how function is encoded into disordered sequences using a combination of computational and experimental approaches
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David M. Holtzman, M.D.
- Cellular and Molecular studies of Alzheimer’s disease
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Michael J. Holtzman, M.D.
- Pathogenesis and new therapeutics for viral infection and post-viral disease
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Jianghui Hou, Ph.D.
- Cell-cell junctions that form epithelial barriers to ions and solutes critical for normal kidney functions
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Paul W. Hruz, Ph.D., M.D.
- Structural Biology and Regulation of Glucose Transport; Molecular Mechanisms Leading to Insulin Resistance
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James J. Hsieh, M.D., Ph.D.
- Integrate contemporary research tools to quickly improve human cancer care
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Hongzhen Hu, Ph.D.
- Neuroimmune mechanisms of sensory processing at barrier surfaces
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James E. Huettner, Ph.D.
- Glutamate receptors, synaptic transmission and stem cell differentiation
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Jing W. Hughes, M.D., Ph.D.
- The research focuses on islet biology and aims to improve diabetes care
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Scott J. Hultgren, Ph.D.
- Pilus and amyloid fiber formation in bacteria: Structure, function and role in diseases of the urinary tract
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Shin-ichiro Imai, M.D., Ph.D.
- Understanding the molecular mechanism of aging and longevity in mammals
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Joseph Ippolito, M.D., Ph.D.
- Sex differences in cancer metabolism
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Meredith E. Jackrel, Ph.D.
- Protein folding and misfolding, and the engineering and application of protein disaggregases to reverse misfolding
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James W. Janetka, Ph.D.
- The rational structure-based drug design and synthesis for cancer and infectious disease
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Silvia Jansen, Ph.D.
- we study the molecular mechanisms that regulate the architecture, dimensions and dynamics of actin filament networks, and tune them to support essential cellular functions including cell migration, intracellular trafficking and cytokinesis.
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Celeste M. Karch, Ph.D.
- Understanding the molecular and cellular mechanisms underlying tauopathies
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David Kast, Ph.D.
- Understand fundamental cellular and molecular mechanisms that drive the biogenesis and dynamics of intracellular membrane compartments
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Charles Kaufman, MD, Ph.D.
- Understanding and modifying the mechanisms controlling the onset of melanoma cancer by integrating zebrafish models and human disease
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Daniel Kerschensteiner, M.D.
- Neural circuit assembly and visual processing in the retina and the brain
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